Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588996 | 0.73 | ACHE (0.38) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL2975788 | 0.71 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL10723055 | 0.71 | CYP4F2 (0.58) | CYP4F2CYP4A11KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27565063 | 0.70 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL4285044 | 0.69 | TSHR (0.54) | CYP4F2CYP4A11KDM4EALDH1A1HPGD | |
| SCHEMBL7262515 | 0.69 | AKT1 (0.36) | KDM4EALDH1A1TSHRGAARAB9A | |
| SCHEMBL9345335 | 0.68 | CYP4F2 (0.56) | CYP4F2CYP4A11TNFAKT1 | |
| SCHEMBL8570715 | 0.68 | CYP4F2 (0.60) | CYP4F2CYP4A11TSHRNPSR1GAA | |
| SCHEMBL10724743 | 0.68 | MTNR1A (0.43) | KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL27512245 | 0.68 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101284773-A | Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient | ONO PHARMACEUTICAL CO (JP) | 2008-10-15 | — | — | CN | disclosed |
| CN-1551866-A | Carboxylic acid derivative compounds and drugs containing these compounds as active ingredient | СҰҩƷ��ҵ��ʽ���� | 2004-12-01 | — | — | CN | disclosed |