Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379293 | 0.81 | GRM6 (0.40) | GRM6CISD2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL27379121 | 0.79 | TAS2R14 (0.41) | CFTRLMNANOTUMCES2TAS2R14 | |
| SCHEMBL30755336 | 0.79 | TAS2R14 (0.41) | CFTRLMNANOTUMCES2TAS2R14 | |
| SCHEMBL27379419 | 0.78 | GRM6 (0.40) | GRM6LMNACISD2CYP2C9CYP2C19 | |
| SCHEMBL27588996 | 0.75 | ACHE (0.38) | GRM6POLBCISD2CYP2C19 | |
| SCHEMBL22207920 | 0.74 | SCN10A (0.37) | NR1H2NR1H3RXRAGRM6LMNA | |
| SCHEMBL13529945 | 0.74 | NOTUM (0.48) | NR1H2NR1H3RXRACFTRLMNA | |
| SCHEMBL22207925 | 0.72 | SCN10A (0.46) | NR1H2NR1H3RXRAGRM6 | |
| SCHEMBL31697169 | 0.72 | SCN10A (0.46) | NR1H2NR1H3RXRAGRM6 | |
| SCHEMBL30755472 | 0.72 | IDH1 (0.35) | NR1H2NR1H3RXRAGRM6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562016-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |