Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17054139 | 0.87 | GRM6 (0.39) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL2730411 | 0.84 | GRM6 (0.49) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL16680460 | 0.83 | THRB (0.40) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7861823 | 0.79 | GRM6 (0.39) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL2718238 | 0.78 | CA12 (0.48) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4644479 | 0.76 | GRM6 (0.43) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10982569 | 0.76 | GRM6 (0.43) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6830109 | 0.76 | POLB (0.45) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL976497 | 0.75 | MMP2 (0.47) | GRM6MAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3188087 | 0.75 | KDM4E (0.50) | MAPK1KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622243-A | Sulfonamide derivative | ASAHI KASEI PHARMA CORP | 2010-01-06 | — | — | CN | disclosed |