Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394759 | 0.86 | ALDH1A1 (0.33) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL12462040 | 0.82 | FDPS (0.39) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL3347182 | 0.81 | MEN1 (0.31) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL3347187 | 0.81 | LOXL2 (0.33) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL3350511 | 0.81 | HRH3 (0.34) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL13333690 | 0.78 | MEN1 (0.32) | ADRB2ADRB1ADRB3 | |
| SCHEMBL130211 | 0.78 | — | — | |
| SCHEMBL13306238 | 0.77 | — | — | |
| SCHEMBL2629266 | 0.75 | SLC6A3 (0.44) | ALDH1A1 | |
| SCHEMBL20341001 | 0.74 | FBP1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100366605-C | Compounds to treat alzheimer's disease | ELAN PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| CN-1447789-A | Compounds for treating alzheimer's disease | ELAN PHARM INC (US) | 2003-10-08 | — | — | CN | disclosed |