SCHEMBL27595607

SCHEMBL27595607

CCOC(=O)C(F)c1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPSR1 Q6W5P4 3/20 0.47
LMNA P02545 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
KDM4E B2RXH2 2/20 0.45
GAA P10253 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
ALOX12 P18054 1/20 0.44
CCR6 P51684 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
KDM4C Q9H3R0 1/20 0.44
CASP3 P42574 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
SENP7 Q9BQF6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28224535 0.85 ESR1 (0.52) MAPTKMT2ALMNACYP1A2CYP2C9
SCHEMBL7987182 0.84 OPRM1 (0.38) MEN1KMT2ALMNATDP1
SCHEMBL11260308 0.84 LMNA (0.53) MAPTMEN1KMT2ALMNACYP1A2
SCHEMBL18610656 0.84 MAPT (0.46) MAPTMEN1KMT2ANPSR1LMNA
SCHEMBL2799224 0.84 CA12 (0.50) MAPTNPSR1LMNACYP1A2KDM4E
SCHEMBL324209 0.83 MMP8 (0.56) MEN1KMT2ALMNACYP1A2CYP2C9
SCHEMBL2314909 0.83 KLK7 (0.49) MAPTMEN1KMT2ANPSR1LMNA
SCHEMBL2400228 0.83 MMP8 (0.56) MEN1KMT2ALMNACYP1A2CYP2C9
SCHEMBL1772316 0.83 MMP8 (0.51) MAPTMEN1KMT2ANPSR1LMNA
SCHEMBL4290959 0.83 MMP8 (0.56) MEN1KMT2ALMNACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1436463-A Synthesis process of primisulfuron-methy and other fluoric hebicide XIAO SHENCHU (CN) 2003-08-20 CN claimed