Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581069 | 0.85 | LSS (0.36) | LSS | |
| SCHEMBL27578365 | 0.83 | KCNH2 (0.40) | LSSCYP1A2CYP2C9CHRM2CHRM4 | |
| SCHEMBL27596290 | 0.74 | LSS (0.34) | LSS | |
| SCHEMBL7204665 | 0.73 | LSS (0.44) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7204663 | 0.73 | LSS (0.44) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL22697436 | 0.71 | CYP1A2 (0.43) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL19636628 | 0.71 | MEN1 (0.44) | — | |
| SCHEMBL7210575 | 0.71 | LSS (0.37) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7204660 | 0.71 | LSS (0.37) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6448156 | 0.69 | ALDH1A1 (0.36) | FOXM1CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100455566-C | Novel derivatives of aminocyclohexane | HOFFMANN LA ROCHE (CH) | 2009-01-28 | — | — | CN | disclosed |
| CN-1468214-A | Novel derivatives of aminocyclohexane | - | 2004-01-14 | — | — | CN | disclosed |