Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27596281 | 0.87 | ALDH1A1 (0.35) | MAOAMAOBMEN1ALDH1A1LMNA | |
| Ethoxycarbonyl Group SCHEMBL27615054 | 0.86 | SIRT2 (0.43) | MAOAMAOBMEN1ALDH1A1LMNA | |
| Ethoxycarbonyl Group SCHEMBL27596280 | 0.85 | FTO (0.35) | MAOAMAOBMEN1ALDH1A1LMNA | |
| Ethoxycarbonyl Group SCHEMBL28754011 | 0.81 | KMT2A (0.48) | MAOAMAOBMEN1ALDH1A1LMNA | |
| SCHEMBL30940293 | 0.72 | ALDH1A1 (0.40) | MAOAMAOBMEN1ALDH1A1LMNA | |
| Chromone SCHEMBL27464281 | 0.69 | MAOB (0.64) | MAOAMAOBMEN1ALDH1A1LMNA | |
| SCHEMBL30771800 | 0.68 | PTPN1 (0.47) | MAOAMAOBMEN1ALDH1A1LMNA | |
| SCHEMBL30026940 | 0.68 | ALDH1A1 (0.39) | MAOAMAOBMEN1ALDH1A1LMNA | |
| SCHEMBL27163023 | 0.68 | ALDH1A1 (0.39) | MAOAMAOBMEN1ALDH1A1LMNA | |
| SCHEMBL28079940 | 0.68 | ALDH1A1 (0.59) | MEN1ALDH1A1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610671-A | Therapeutic quinoline compounds having 5-HT-antagonistic properties | ASTRAZENECA AB (SE) | 2005-04-27 | — | — | CN | disclosed |
| CN-1608054-A | Therapeutic quinolone compounds having 5-HT-antagonistic properties | ASTRAZENECA AB (SE) | 2005-04-20 | — | — | CN | disclosed |