Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 7/20 | 0.34 |
| ▸ | MAOA | P21397 | 5/20 | 0.34 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27615054 | 0.88 | SIRT2 (0.43) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| Ethoxycarbonyl Group SCHEMBL27596274 | 0.87 | MAOA (0.33) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| Ethoxycarbonyl Group SCHEMBL27596280 | 0.87 | FTO (0.35) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| SCHEMBL30940293 | 0.86 | ALDH1A1 (0.40) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| Ethoxycarbonyl Group SCHEMBL28754011 | 0.83 | KMT2A (0.48) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| Ethoxycarbonyl Group SCHEMBL27615051 | 0.79 | CDK2 (0.41) | MEN1KMT2ASIGMAR1 | |
| Chromone SCHEMBL27464281 | 0.71 | MAOB (0.64) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| SCHEMBL27596282 | 0.70 | SIRT2 (0.46) | MAOBCSNK2A2CSNK2BCSNK2A1SMN1; SMN2 | |
| SCHEMBL28471407 | 0.70 | CSNK2A2 (0.50) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| SCHEMBL30771800 | 0.70 | PTPN1 (0.47) | ALDH1A1HPGDMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610671-A | Therapeutic quinoline compounds having 5-HT-antagonistic properties | ASTRAZENECA AB (SE) | 2005-04-27 | — | — | CN | disclosed |
| CN-1608054-A | Therapeutic quinolone compounds having 5-HT-antagonistic properties | ASTRAZENECA AB (SE) | 2005-04-20 | — | — | CN | disclosed |