Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.42 |
| ▸ | ACACA | Q13085 | 10/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759728 | 0.88 | ACACB (0.37) | ACACBACACA | |
| SCHEMBL16588264 | 0.86 | ACACB (0.38) | ACACBACACA | |
| SCHEMBL2759736 | 0.86 | ACACB (0.38) | ACACBACACA | |
| SCHEMBL561396 | 0.86 | MGLL (0.35) | — | |
| SCHEMBL2759719 | 0.83 | TDP2 (0.34) | TDP2 | |
| SCHEMBL2759714 | 0.81 | GAA (0.39) | — | |
| SCHEMBL15182378 | 0.80 | MAPK1 (0.36) | HSD11B1 | |
| SCHEMBL3434210 | 0.79 | ACACB (0.43) | ACACBACACABRD4HSD11B1 | |
| SCHEMBL15182377 | 0.79 | ALOX15 (0.43) | — | |
| SCHEMBL15300237 | 0.79 | CES1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352375-B1 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-25 | — | — | EP | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2010052161-A2 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | DDT, CAT, HDHD5 | ACACB 704/4885ACACA 1250/4885BRD4 3639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.