Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752185 | 0.88 | SNCA (0.55) | HDAC8HDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6718542 | 0.84 | NAAA (0.73) | HDAC8HDAC6RAB9ANPC1ALDH1A1 | |
| SCHEMBL5049475 | 0.82 | NPC1 (0.56) | HDAC6RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27619596 | 0.82 | NAAA (0.74) | HDAC8RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1853875 | 0.81 | ALDH1A1 (0.55) | HDAC6RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5044262 | 0.81 | L3MBTL1 (0.62) | HDAC8HDAC6SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5045782 | 0.81 | HDAC8 (0.62) | HDAC8HDAC6SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL12158624 | 0.81 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1853826 | 0.81 | MLYCD (0.64) | HDAC8SMN1; SMN2ALDH1A1MAPTNAAA | |
| SCHEMBL14842406 | 0.81 | HPGD (0.62) | HDAC8HDAC6RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |