Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125535 | 0.81 | ALDH1A1 (0.38) | TLR8HTTCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL28142079 | 0.76 | ALKBH5 (0.40) | TLR8HTTALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL16046643 | 0.74 | ALKBH5 (0.39) | TLR8HTTALDH1A1KDM4EMAPT | |
| SCHEMBL15465842 | 0.73 | ALDH1A1 (0.56) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| SCHEMBL29129518 | 0.72 | CNR2 (0.46) | TLR8CNR2 | |
| SCHEMBL12261737 | 0.72 | HTT (0.41) | TLR8HTTCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL28268495 | 0.69 | PLA2G2A (0.41) | CYP1A2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL27604178 | 0.68 | MEN1 (0.38) | TLR8HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL24074349 | 0.68 | ELANE (0.41) | CYP1A2ALDH1A1KMT2AHPGDMAPK1 | |
| SCHEMBL19271262 | 0.68 | RAB9A (0.51) | HTTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013512-A1 | N-[2-SUBSTITUTED-3-(2-AMINOETHYL)-1H-INDOL-5-YL]-AMIDES: NEW 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |