Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590506 | 0.91 | NPC1 (0.32) | NPC1LMNATP53HPGDRAB9A | |
| SCHEMBL27608930 | 0.89 | NPC1 (0.32) | NPC1LMNATP53HPGDRAB9A | |
| SCHEMBL27590523 | 0.81 | BCHE (0.30) | — | |
| SCHEMBL7766488 | 0.80 | HTT (0.35) | TP53TSHRHTTP2RX4 | |
| SCHEMBL27756879 | 0.78 | — | — | |
| SCHEMBL28756718 | 0.77 | ALDH1A1 (0.37) | NPC1LMNATP53HPGDRAB9A | |
| SCHEMBL27629689 | 0.77 | MTNR1A (0.32) | HPGDTSHRP2RX4 | |
| SCHEMBL27749571 | 0.76 | — | — | |
| SCHEMBL28891502 | 0.76 | NPC1 (0.32) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL27629478 | 0.76 | HDAC3 (0.33) | LMNAHPGDP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |