Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590506 | 0.95 | NPC1 (0.32) | NPC1LMNATP53HPGDRAB9A | |
| SCHEMBL27608922 | 0.89 | NPC1 (0.33) | NPC1LMNATP53HPGDRAB9A | |
| SCHEMBL27590524 | 0.85 | NPC1 (0.32) | NPC1LMNATP53HPGDRAB9A | |
| SCHEMBL27590523 | 0.84 | BCHE (0.30) | — | |
| SCHEMBL27629478 | 0.81 | HDAC3 (0.33) | LMNAHPGDPRKCGPRKCBPRKCA | |
| SCHEMBL27610601 | 0.81 | PPARG (0.41) | LMNAPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL27629689 | 0.79 | MTNR1A (0.32) | HPGDPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL27590551 | 0.79 | GRIA1 (0.31) | — | |
| SCHEMBL27590541 | 0.78 | NISCH (0.32) | — | |
| SCHEMBL27608978 | 0.78 | TSHR (0.36) | LMNATP53SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |