Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28890966 | 0.79 | EBP (0.34) | LMNAMAPTL3MBTL1 | |
| SCHEMBL28417337 | 0.79 | CES1 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28421653 | 0.77 | ICMT (0.37) | NPC1RAB9AMAPT | |
| SCHEMBL28260614 | 0.77 | LMNA (0.35) | NPC1RAB9ALMNATP53MAPT | |
| SCHEMBL28409337 | 0.76 | MAPT (0.40) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL28415259 | 0.76 | MAPT (0.36) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL27608922 | 0.76 | NPC1 (0.33) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL28409339 | 0.75 | MAPT (0.43) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28846643 | 0.74 | NPC1 (0.33) | NPC1RAB9ALMNATP53MAPT | |
| SCHEMBL28413739 | 0.74 | MAPT (0.40) | NPC1RAB9ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303065-B | N- (arylaminoethyl) -3, 1-benzoxazine-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2021-11-16 | — | — | CN | claimed |
| CN-111303065-A | N- (arylaminoethyl) -3, 1-benzoxazine-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2020-06-19 | — | — | CN | claimed |
| CN-111303065-B | N- (arylaminoethyl) -3, 1-benzoxazine-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-111303065-A | N- (arylaminoethyl) -3, 1-benzoxazine-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2020-06-19 | — | — | CN | disclosed |