Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629478 | 0.96 | HDAC3 (0.33) | MTNR1AALDH1A1P2RX4HPGDPRKCG | |
| SCHEMBL27610601 | 0.85 | PPARG (0.41) | MTNR1AALDH1A1P2RX4PRKCGPRKCB | |
| SCHEMBL28756718 | 0.85 | ALDH1A1 (0.37) | MTNR1AALDH1A1P2RX4HPGDMEN1 | |
| SCHEMBL27590506 | 0.80 | NPC1 (0.32) | HPGDTSHR | |
| SCHEMBL27590523 | 0.80 | BCHE (0.30) | — | |
| SCHEMBL27608930 | 0.79 | NPC1 (0.32) | HPGDPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL27610373 | 0.77 | PRKCG (0.31) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL27608922 | 0.77 | NPC1 (0.33) | P2RX4HPGDTSHR | |
| SCHEMBL7766488 | 0.76 | HTT (0.35) | ALDH1A1P2RX4KMT2AL3MBTL1P2RX1 | |
| SCHEMBL27609196 | 0.74 | SIGMAR1 (0.47) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |