Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609187 | 0.90 | CREBBP (0.34) | NISCH | |
| SCHEMBL27590541 | 0.84 | NISCH (0.32) | NISCHMAPT | |
| SCHEMBL27590556 | 0.84 | NISCH (0.36) | ATMALDH1A1NISCHCYP3A4MAPT | |
| SCHEMBL27590506 | 0.82 | NPC1 (0.32) | TSHRNPSR1LMNASMN1; SMN2TP53 | |
| SCHEMBL27934603 | 0.80 | L3MBTL1 (0.37) | TSHRLMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27609039 | 0.79 | LMNA (0.32) | LMNA | |
| SCHEMBL27608930 | 0.78 | NPC1 (0.32) | NPSR1LMNASMN1; SMN2TP53 | |
| SCHEMBL27590551 | 0.77 | GRIA1 (0.31) | — | |
| SCHEMBL27590539 | 0.76 | GSK3B (0.33) | ALDH1A1 | |
| SCHEMBL27609127 | 0.76 | NISCH (0.32) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |