Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590539 | 0.85 | GSK3B (0.33) | GRIA1GRIA2GRIA3GRIA4HTR1A | |
| SCHEMBL27609187 | 0.85 | CREBBP (0.34) | — | |
| SCHEMBL27590506 | 0.83 | NPC1 (0.32) | — | |
| SCHEMBL27934675 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL27608930 | 0.79 | NPC1 (0.32) | — | |
| SCHEMBL27608978 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL27590541 | 0.77 | NISCH (0.32) | — | |
| SCHEMBL27590556 | 0.74 | NISCH (0.36) | — | |
| SCHEMBL27608922 | 0.74 | NPC1 (0.33) | — | |
| SCHEMBL27934603 | 0.74 | L3MBTL1 (0.37) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |