Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590541 | 0.90 | NISCH (0.32) | — | |
| SCHEMBL27590551 | 0.85 | GRIA1 (0.31) | GRIA1GRIA2GRIA3GRIA4HTR1A | |
| SCHEMBL27609187 | 0.84 | CREBBP (0.34) | — | |
| SCHEMBL27590506 | 0.82 | NPC1 (0.32) | NPC1HTTRAB9A | |
| SCHEMBL27934675 | 0.80 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL27608930 | 0.78 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL27608978 | 0.76 | TSHR (0.36) | ALDH1A1 | |
| SCHEMBL27590556 | 0.73 | NISCH (0.36) | ALDH1A1 | |
| SCHEMBL27608922 | 0.73 | NPC1 (0.33) | NPC1HTTRAB9A | |
| SCHEMBL27934603 | 0.73 | L3MBTL1 (0.37) | ALDH1A1HTTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |