Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MGAM | O43451 | 3/20 | 0.46 |
| ▸ | SI | P14410 | 3/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678945 | 0.88 | GPR84 (0.52) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL946518 | 0.80 | MEN1 (0.52) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29678756 | 0.79 | GAA (0.51) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29678938 | 0.78 | GAA (0.50) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29678809 | 0.77 | NR3C1 (0.46) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL28287416 | 0.75 | MAPT (0.49) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29678752 | 0.74 | MAPT (0.52) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29678900 | 0.74 | NR3C1 (0.46) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL28587999 | 0.73 | L3MBTL1 (0.62) | NR3C1GAAMGAMSIMGAM2 | |
| SCHEMBL29678784 | 0.72 | NR3C1 (0.56) | NR3C1GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |