Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609196 | 0.93 | SIGMAR1 (0.47) | ACHEKDM1ACHRM2CHRM4CHRM5 | |
| SCHEMBL27590501 | 0.83 | CHRM1 (0.48) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL27609108 | 0.78 | CHRM1 (0.50) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL27608922 | 0.75 | NPC1 (0.33) | LMNATP53 | |
| SCHEMBL27609010 | 0.74 | KDM1A (0.51) | ACHEKDM1ACHRM2CHRM4CHRM5 | |
| SCHEMBL7766488 | 0.74 | HTT (0.35) | TP53 | |
| SCHEMBL27590523 | 0.72 | BCHE (0.30) | — | |
| SCHEMBL27590506 | 0.72 | NPC1 (0.32) | LMNATP53 | |
| SCHEMBL27756879 | 0.72 | — | — | |
| SCHEMBL28756718 | 0.71 | ALDH1A1 (0.37) | LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |