Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609192 | 0.93 | ACHE (0.43) | SIGMAR1KDM1ACHRM2CHRM4CHRM5 | |
| SCHEMBL27609108 | 0.85 | CHRM1 (0.50) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL27590501 | 0.79 | CHRM1 (0.48) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL27608930 | 0.78 | NPC1 (0.32) | LMNA | |
| SCHEMBL27590523 | 0.76 | BCHE (0.30) | — | |
| SCHEMBL27590506 | 0.76 | NPC1 (0.32) | LMNA | |
| SCHEMBL27610601 | 0.76 | PPARG (0.41) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27629478 | 0.76 | HDAC3 (0.33) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27629689 | 0.74 | MTNR1A (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27608922 | 0.73 | NPC1 (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |