Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425534 | 0.88 | ALDH1A1 (0.42) | KMT2AMEN1CYP1A2ERBB2FYN | |
| SCHEMBL246709 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL8458747 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL4600933 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL19999169 | 0.71 | KMT2A (0.41) | KMT2AMEN1CYP1A2ALDH1A1HPGD | |
| SCHEMBL15620820 | 0.71 | NCEH1 (0.62) | CYP1A2ALDH1A1HPGDMAPTNCEH1 | |
| SCHEMBL16241709 | 0.71 | CYP1A2 (0.52) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL6511350 | 0.71 | ALDH1A1 (0.42) | KMT2AMEN1CYP1A2ALDH1A1HPGD | |
| Pyrene SCHEMBL4782088 | 0.70 | KMT2A (0.50) | KMT2AMEN1CYP1A2ALDH1A1HPGD | |
| SCHEMBL5057152 | 0.70 | MAOB (0.52) | KMT2AMEN1CYP1A2MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639569-B | Methods and compositions for inducing an immune response | CHEMOCENTRYX | 2012-09-05 | — | — | CN | disclosed |
| CN-102023220-A | Methods of diagnosing cervical cancer | ARBOR VITA CORP | 2011-04-20 | — | — | CN | disclosed |
| CN-1695058-B | method for diagnosing cervical cancer | ARBOR VITA CORP | 2011-04-13 | — | — | CN | disclosed |
| CN-1695058-A | method for diagnosing cervical cancer | ARBOR VITA CORP (US) | 2005-11-09 | — | — | CN | disclosed |
| CN-1639569-A | Methods and compositions for inducing an immune response | CHEMOCENTRYX INC (US) | 2005-07-13 | — | — | CN | disclosed |