Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.47 |
| ▸ | IL1B | P01584 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724695 | 0.83 | HSD11B1 (0.58) | P2RX7HSD11B1MAPT | |
| SCHEMBL3529974 | 0.83 | HPGD (0.67) | HPGDCNR1MEN1KMT2ATDP1 | |
| SCHEMBL28753564 | 0.82 | HPGD (0.50) | HPGDCNR1KMT2APLAAT3PLAAT5 | |
| SCHEMBL1344012 | 0.81 | P2RX7 (0.44) | P2RX7KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5774639 | 0.78 | HPGD (0.47) | HPGDCNR1MEN1KMT2ATDP1 | |
| SCHEMBL2774093 | 0.78 | HIF1A (0.43) | ALDH1A1KDM4E | |
| SCHEMBL5045620 | 0.78 | MEN1 (0.50) | HPGDP2RX7HSD11B1MEN1KMT2A | |
| SCHEMBL29673144 | 0.78 | MEN1 (0.50) | HPGDP2RX7HSD11B1MEN1KMT2A | |
| SCHEMBL5110287 | 0.77 | P2RX7 (0.46) | HPGDCNR1P2RX7PLAAT3PLAAT5 | |
| SCHEMBL20362255 | 0.77 | MTNR1A (0.52) | HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589153-A | Prevention or treatment of urinary disorders | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-03-02 | — | — | CN | disclosed |