Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12973608 | 0.82 | LPAR1 (0.72) | LPAR1LPAR3PTGS1ALDH1A1RAB9A | |
| SCHEMBL6003 | 0.81 | LPAR1 (0.54) | LPAR1LPAR3KMT2AKDM4EHTT | |
| SCHEMBL9903838 | 0.81 | NPSR1 (0.48) | KMT2AKDM4EHTTMEN1ALDH1A1 | |
| SCHEMBL2761396 | 0.78 | PTGS1 (0.58) | PTGS1KMT2AKDM4EHTTMEN1 | |
| SCHEMBL4304 | 0.78 | RAB9A (0.40) | LPAR1LPAR3KMT2AKDM4EHTT | |
| SCHEMBL4029460 | 0.76 | NPSR1 (0.61) | PTGS1KMT2AKDM4EHTTMEN1 | |
| SCHEMBL4035675 | 0.76 | MAPT (0.67) | LPAR1LPAR3PTGS1KMT2AKDM4E | |
| SCHEMBL19742000 | 0.74 | PTGS2 (0.51) | PTGS1KMT2AMEN1ALDH1A1NR1H4 | |
| SCHEMBL2761365 | 0.73 | PTGS1 (0.62) | PTGS1KMT2AKDM4EHTTMEN1 | |
| SCHEMBL4034308 | 0.72 | KDM4E (0.49) | LPAR1LPAR3PTGS1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141768-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |