Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | IAPP | P10997 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5877556 | 0.78 | GABRA1 (0.51) | GABRA1GABRB2IAPPTRPA1ELANE | |
| SCHEMBL11284851 | 0.75 | GABRA1 (0.53) | GABRA1GABRB2IAPPTRPA1ELANE | |
| SCHEMBL1053654 | 0.73 | GABRA1 (0.79) | GABRA1GABRB2IAPPTRPA1ELANE | |
| SCHEMBL29812362 | 0.73 | GABRA1 (0.59) | GABRA1GABRB2IAPPTRPA1ELANE | |
| SCHEMBL13907974 | 0.70 | SIGMAR1 (0.44) | TRPA1TDP1 | |
| SCHEMBL632694 | 0.70 | GABRA1 (0.55) | GABRA1GABRB2 | |
| SCHEMBL10430786 | 0.67 | GABRA1 (0.50) | GABRA1GABRB2IAPPTRPA1ADAMTS4 | |
| SCHEMBL5877562 | 0.67 | GABRA1 (0.51) | GABRA1GABRB2ELANECTSGALDH1A1 | |
| SCHEMBL6700169 | 0.66 | IAPP (0.50) | GABRA1GABRB2IAPPELANECTSG | |
| SCHEMBL31498329 | 0.66 | TRPA1 (0.45) | GABRA1GABRB2IAPPTRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574932-A | Method for producing modified conjugated diene rubber, and rubber composition | JSR CORP | 2012-07-11 | — | — | CN | disclosed |
| CN-100436487-C | Polymer well compatible with inorganic fillers | ASAHI CHEMICAL CORP (JP) | 2008-11-26 | — | — | CN | disclosed |
| CN-100349962-C | Siloxane copolymer, making method, and thermosetting resin composition | SHINETSU CHEMICAL CO (JP) | 2007-11-21 | — | — | CN | disclosed |
| CN-1894288-A | Polymer well compatible with inorganic fillers | ASAHI CHEMICAL CORP (JP) | 2007-01-10 | — | — | CN | disclosed |
| CN-1583835-A | Siloxane copolymer, making method, and thermosetting resin composition | SHINETSU CHEMICAL CO (JP) | 2005-02-23 | — | — | CN | disclosed |