Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 8/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27597014 | 0.81 | MEN1 (0.47) | ATMCTRB1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL18157218 | 0.78 | ATM (0.57) | ATMCTRB1CTSLCTSSCTSK | |
| SCHEMBL9834149 | 0.77 | ATM (0.58) | ATMCTRB1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL9830055 | 0.76 | CTSL (0.50) | ATMCTRB1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL6501321 | 0.76 | CASP1 (0.56) | ATMCYP3A4CTSLCTSSCTSK | |
| SCHEMBL6500768 | 0.76 | CASP1 (0.56) | ATMCYP3A4CTSLCTSSCTSK | |
| SCHEMBL29951738 | 0.75 | CTRB1 (0.49) | ATMCTRB1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL6841165 | 0.75 | CTSS (0.61) | ATMCTRB1CTSLCTSSCTSK | |
| SCHEMBL15691156 | 0.75 | CTSS (0.61) | ATMCTRB1CTSLCTSSCTSK | |
| SCHEMBL16824022 | 0.75 | SYK (0.61) | ATMCTRB1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100436412-C | Method for preparing relative amino alcohol by borohydride-acid reduction system reducing amino ketone derivative | UNIV XIAMEN (CN) | 2008-11-26 | — | — | CN | disclosed |
| CN-1587259-A | Method for preparing relative amino alcohol by borohydride-acid reduction system reducing amino ketone derivative | UNIV XIAMEN (CN) | 2005-03-02 | — | — | CN | disclosed |