Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.52 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037126 | 0.89 | LNPEP (0.55) | CTSLMAPTTDP1POLBLNPEP | |
| SCHEMBL22384242 | 0.89 | LNPEP (0.55) | CTSLMAPTTDP1POLBLNPEP | |
| SCHEMBL3928164 | 0.87 | LNPEP (0.67) | CTSLTSHRLNPEPMDM4MDM2 | |
| SCHEMBL3928165 | 0.87 | LNPEP (0.67) | CTSLTSHRLNPEPMDM4MDM2 | |
| SCHEMBL7703695 | 0.87 | LNPEP (0.53) | CTSLMAPTTDP1POLBTSHR | |
| SCHEMBL19485398 | 0.85 | MAPT (0.59) | CTSLMAPTTDP1POLBITGA4 | |
| SCHEMBL3935180 | 0.85 | CTSL (0.62) | CTSLTSHRLNPEPMDM4MDM2 | |
| SCHEMBL1796825 | 0.85 | CTSL (0.62) | CTSLTSHRLNPEPMDM4MDM2 | |
| SCHEMBL30064651 | 0.85 | CTSL (0.62) | CTSLTSHRLNPEPMDM4MDM2 | |
| SCHEMBL1784498 | 0.85 | CTSL (0.62) | CTSLTSHRLNPEPMDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639141-A | Novel thiadiazoles and oxadiazoles and their use as phosphodiesterase-7 inhibitors | WARNER LAMBERT CO (US) | 2005-07-13 | — | — | CN | disclosed |