Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | INMT | O95050 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31502955 | 0.80 | MAPT (0.55) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL2101375 | 0.76 | USP2 (0.40) | SMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL13731454 | 0.71 | NAAA (0.47) | LMNAMAPTKMT2APOLBINMT | |
| SCHEMBL3080090 | 0.71 | — | — | |
| SCHEMBL30874872 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL7752266 | 0.69 | POLB (0.41) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8157077 | 0.69 | NAAA (0.56) | KMT2APOLBTDP1 | |
| SCHEMBL1231766 | 0.68 | LMNA (0.55) | ALDH1A1LMNAMAPTKMT2ATSHR | |
| SCHEMBL9586348 | 0.68 | NAAA (0.51) | ALDH1A1MAPTTSHRHTTRECQL | |
| SCHEMBL5569327 | 0.68 | FAAH (0.51) | ALDH1A1SMN1; SMN2MAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100369902-C | N-alkoxide oxo-2-triazolidone derivative, its preparation and use | UNIV ZHEJIANG POLYTECHNIC (CN) | 2008-02-20 | — | — | CN | disclosed |
| CN-1644579-A | N-alkoxide oxo-2-triazolidone derivative, its preparation and use | UNIV ZHEJIANG POLYTECHNIC (CN) | 2005-07-27 | — | — | CN | disclosed |