Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58881 | 0.81 | LMNA (0.65) | HPGDLMNAMAPK1CES2CES1 | |
| SCHEMBL9221845 | 0.81 | LMNA (0.65) | HPGDLMNAMAPK1CES2CES1 | |
| SCHEMBL26259 | 0.81 | LMNA (0.65) | HPGDLMNAMAPK1CES2CES1 | |
| SCHEMBL890219 | 0.81 | LMNA (0.65) | HPGDLMNAMAPK1CES2CES1 | |
| SCHEMBL31223166 | 0.79 | L3MBTL1 (0.52) | HPGDLMNAMAPK1CES2CES1 | |
| Water SCHEMBL27778930 | 0.79 | LMNA (0.62) | HPGDLMNAMAPK1CES2CES1 | |
| Mandelic Acid SCHEMBL2689157 | 0.79 | LMNA (0.86) | HPGDLMNAMAPK1CES2CES1 | |
| SCHEMBL4647083 | 0.78 | BRD4 (0.52) | HPGDLMNACES2CES1CYP2D6 | |
| SCHEMBL4641885 | 0.78 | HDAC3 (0.42) | HPGDLMNACES2CES1ALDH1A1 | |
| SCHEMBL18419227 | 0.78 | HPGD (1.00) | HPGDLMNAMAPK1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511359-A | Non-steroidal selective glucocorticoid receptor agonist modulators (SEGRAM) and uses thereof | IGBMC研究协会(ARI) | 2020-08-07 | — | — | CN | disclosed |
| CN-100519671-C | Film-forming polymer and antifouling paint | JOTUN AS (NO) | 2009-07-29 | — | — | CN | disclosed |
| CN-1643085-A | Film-forming polymer and antifouling paint | JOTUN AS (NO) | 2005-07-20 | — | — | CN | disclosed |