SCHEMBL26259

SCHEMBL26259

CC(=O)C(O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.65
MAPK1 P28482 1/20 0.65
HPGD P15428 1/20 0.63
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
SRC P12931 2/20 0.48
CYP2D6 P10635 1/20 0.48
KMT2A Q03164 1/20 0.45
NAAA Q02083 2/20 0.44
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9221845 1.00 LMNA (0.65) LMNAMAPK1HPGDCES2CES1
SCHEMBL890219 1.00 LMNA (0.65) LMNAMAPK1HPGDCES2CES1
SCHEMBL30785017 0.87 PTGS2 (0.57) LMNAMAPK1HPGDCES2CES1
Mandelic Acid SCHEMBL2689157 0.83 LMNA (0.86) LMNAMAPK1HPGDCES2CES1
SCHEMBL11221250 0.82 RXRA (0.51) LMNAMAPK1HPGDCES2CES1
SCHEMBL27619969 0.81 HPGD (0.64) LMNAMAPK1HPGDCES2CES1
Mandelic Acid SCHEMBL7279536 0.80 LMNA (0.90) LMNAMAPK1HPGDCES2CES1
Mandelic Acid SCHEMBL5313046 0.79 LMNA (1.00) LMNAMAPK1HPGDCES2CES1
SCHEMBL4882534 0.79 LMNA (0.56) LMNAMAPK1HPGDCES2CES1
Mandelic Acid SCHEMBL165161 0.79 LMNA (1.00) LMNAMAPK1HPGDCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 594 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119161802-A Self-crosslinking polyurethane resin and application thereof, single-component solvent-free polyurethane waterproof coating and preparation method thereof 南通科顺建筑新材料有限公司 2024-12-20 CN claimed
CN-118755407-A Low-climbing high-residue release agent, preparation method thereof and release film 江苏斯迪克新材料科技股份有限公司 2024-10-11 CN claimed
CN-118666696-A Synthesis and refining method of meta-hydroxylamine bitartrate 玉门千华制药有限公司 2024-09-20 CN claimed
CN-113784945-A Process for preparing R-phenylacetylcarbinol and beta-aminoalcohols 马拉迪制药有限公司 2021-12-10 CN claimed
CN-107075495-B Lyase, DNA encoding the lyase, vector comprising the DNA, and method for asymmetric synthesis of (S) -phenylacetylcarbinol 于利奇研究中心有限公司 2021-10-29 CN claimed
EP-3160937-B1 A NOVEL METHOD FOR SYNTHESIS OF OPTICALLY PURE BETA-AMINO ALCOHOLS EMBIO LTD (IN) 2020-12-30 EP claimed
WO-2020129087-A1 NOVEL PROCESS FOR THE PREPARATION OF R-PHENYLACETYLCARBINOL AND β-AMINOALCOHOLS MALLADI DRUGS AND PHARMACEUTICALS LTD. (IN) 2020-06-25 WO claimed
CN-111057382-A Synthesis of free radical light/moisture curing organic silicon composition 烟台德邦科技有限公司 2020-04-24 CN claimed
CN-108948475-A A kind of reactive extrursion method improved polyalkene-Lignin Film and preparation method thereof 济宁明升新材料有限公司 2018-12-07 CN claimed
CN-108948689-A A kind of reactive extrursion method polydactyl acid-lignin composite material and preparation method 济宁明升新材料有限公司 2018-12-07 CN claimed
US-6004789-A ISOLATING GENE FROM A PRODUCER ORGANISM AND REPLACING CODON FOR TRYPTOPHAN AT POSITION 1174-1176 TO AN AMINO ACID WITH REDUCED VOLUME RATIO; FOR ENZYME WHICH PRODUCES MAINLY (R)-(-)-PHENYLACETYL CARBINOL; FOR MANUFACTURE OF EPHEDRINE FORSCHUNGSZENTRUM JULICH GMBH (DE) 1999-12-21 US claimed
WO-1999063103-A1 YEAST-BASED PROCESS FOR PRODUCTION OF L-PAC VICTORIA UNIVERSITY OF TECHNOLOGY (AU) 1999-12-09 WO claimed
US-5919834-A THERMOPLASTIC RESIN BLEND ILLINOIS TOOL WORKS INC. (US) 1999-07-06 US claimed
CN-1192244-A Process for obtaining acyloins, pyruvate decarboxylases suitable therefor and their production and DNA sequences of the PDC gene coding them FORSCHUNGSZENTRUM JUELICH GMBH (DE) 1998-09-02 CN claimed
EP-0828841-A2 PROCESS FOR OBTAINING ACYLOINS, PYRUVATE DECARBOXYLASES SUITABLE THEREFOR AND THEIR PRODUCTION AND DNA SEQUENCES OF THE PDC GENE CODING THEM FORSCHUNGSZENTRUM JÜLICH GMBH (DE) 1998-03-18 EP claimed
WO-1996037620-A2 PROCESS FOR OBTAINING ACYLOINS, PYRUVATE DECARBOXYLASES SUITABLE THEREFOR AND THEIR PRODUCTION AND DNA SEQUENCES OF THE PDC GENE CODING THEM Forschungszentrum Jülich GmbH (DE) 1996-11-28 WO claimed
US-5079145-A Culture product of benzaldehyde and pyruvate by mutqginized yeast SYNERGEN ASSOCIATES, INC. (US) 1992-01-07 US claimed
EP-0445129-A4 PROCESS FOR MAKING PHENYL ACETYL CARBINOL (PAC), MICROORGANISMS FOR USE IN THE PROCESS, AND A METHOD FOR PREPARING THE MICROORGANISMS 1991-11-27 EP claimed
EP-0445129-A1 PROCESS FOR MAKING PHENYL ACETYL CARBINOL (PAC), MICROORGANISMS FOR USE IN THE PROCESS, AND A METHOD FOR PREPARING THE MICROORGANISMS SYNERGEN, INC. (US) 1991-09-11 EP claimed
WO-1990004631-A1 PROCESS FOR MAKING PHENYL ACETYL CARBINOL (PAC), MICROORGANISMS FOR USE IN THE PROCESS, AND A METHOD FOR PREPARING THE MICROORGANISMS SYNERGEN, INC. (US) 1990-05-03 WO claimed