Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401659 | 0.86 | HTT (0.37) | MAPTL3MBTL1NPSR1LMNAMAPK1 | |
| SCHEMBL2923501 | 0.84 | MEN1 (0.37) | MAPTL3MBTL1NPSR1LMNAMAPK1 | |
| SCHEMBL2929425 | 0.79 | MAPT (0.32) | MAPTL3MBTL1NPSR1LMNAMAPK1 | |
| SCHEMBL3141869 | 0.77 | HTT (0.33) | MAPTL3MBTL1NPSR1LMNAMAPK1 | |
| SCHEMBL27603443 | 0.69 | SMN1; SMN2 (0.40) | MAPT | |
| SCHEMBL6068973 | 0.69 | ALDH1A1 (0.30) | MAPTALDH1A1 | |
| SCHEMBL27928567 | 0.66 | SMN1; SMN2 (0.37) | MAPTKMT2A | |
| SCHEMBL27603447 | 0.65 | MAPT (0.45) | MAPTLMNAMAPK1HTTALDH1A1 | |
| SCHEMBL6758738 | 0.64 | PKM (0.33) | L3MBTL1HTTALDH1A1PKMKMT2A | |
| SCHEMBL3436156 | 0.63 | ALDH1A1 (0.37) | MAPTL3MBTL1NPSR1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1899247-B | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone derivative, a color coupling agent and a selected surface-active agent | OREAL | 2010-10-13 | — | — | CN | disclosed |
| CN-1899247-A | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolone dervative, a coupling agent and a selected surface-active agent | OREAL (FR) | 2007-01-24 | — | — | CN | disclosed |
| CN-1660033-A | Composition for dyeing keratinous fibers comprising at least one diamino-n,n-dihydropyrazolone derivative | OREAL (FR) | 2005-08-31 | — | — | CN | disclosed |