SCHEMBL27622792

SCHEMBL27622792

N#Cc1c(F)ccc(Sc2ccccc2)c1C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 3/20 0.46
HPGD P15428 2/20 0.46
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
BCL2 P10415 1/20 0.38
PGR P06401 1/20 0.37
AR P10275 1/20 0.37
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30071586 0.89 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EHPGDMAOA
SCHEMBL5074837 0.89 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EHPGDMAOA
SCHEMBL1154522 0.75 MAOA (0.47) ALDH1A1MAPTKDM4EHPGDMAOA
SCHEMBL4323122 0.73 TRPV4 (0.48) ALDH1A1MAPTKDM4EHPGDMEN1
SCHEMBL497284 0.73 KDM4E (0.51) ALDH1A1MAPTKDM4EHPGDMAOA
SCHEMBL28639136 0.73 MAOA (0.46) ALDH1A1MAPTKDM4EHPGDMAOA
SCHEMBL7106251 0.72 MAOA (0.48) ALDH1A1MAPTKDM4EHPGDMAOA
SCHEMBL10826453 0.71 MAOA (0.44) ALDH1A1MAPTKDM4EHPGDMAOA
SCHEMBL1772509 0.71 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EHPGDMAOA
SCHEMBL11326735 0.71 MAOA (0.44) ALDH1A1MAPTKDM4EHPGDMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1680380-A Method for production of halogen-containing phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2005-10-12 CN disclosed