SCHEMBL28639136

SCHEMBL28639136

N#Cc1c(Br)cccc1Sc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.46
MAOB P27338 3/20 0.46
ALDH1A1 P00352 5/20 0.44
MAPT P10636 3/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 2/20 0.40
NSD2 O96028 1/20 0.40
PLA2G1B P04054 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
BCL2 P10415 1/20 0.38
SIRT1 Q96EB6 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
DHFR P00374 1/20 0.35
MCL1 Q07820 1/20 0.35
MAP2K2 P36507 1/20 0.35
MAP2K1 Q02750 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30071586 0.82 ALDH1A1 (0.55) MAOAMAOBALDH1A1MAPTKDM4E
SCHEMBL5074837 0.82 ALDH1A1 (0.55) MAOAMAOBALDH1A1MAPTKDM4E
SCHEMBL497284 0.81 KDM4E (0.51) MAOAMAOBALDH1A1MAPTKDM4E
SCHEMBL11326735 0.80 MAOA (0.44) MAOAMAOBALDH1A1MAPTKDM4E
SCHEMBL1772509 0.80 ALDH1A1 (0.50) MAOAMAOBALDH1A1MAPTKDM4E
SCHEMBL12679735 0.78 MAPT (0.47) MAOAMAOBALDH1A1MAPTKDM4E
SCHEMBL547713 0.78 LMNA (0.46) MAOAMAOBMAPTKDM4EHPGD
SCHEMBL9578982 0.76 MAPT (0.44) ALDH1A1MAPTKDM4EHPGDMAPK1
SCHEMBL1343169 0.75 DYRK1A (0.42) ALDH1A1MAPTKDM4EHPGDMAPK1
SCHEMBL26955887 0.75 ALDH1A1 (0.38) ALDH1A1MAPTKDM4EL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113582908-A Near-ultraviolet organic electroluminescent material based on benzene cyano, preparation method thereof and application thereof in preparing OLED 华南理工大学 2021-11-02 CN claimed
CN-113582908-B Near-ultraviolet organic electroluminescent material based on phenylcyano, preparation method thereof and application thereof in OLED preparation 华南理工大学 2023-09-26 CN disclosed
CN-113582908-A Near-ultraviolet organic electroluminescent material based on benzene cyano, preparation method thereof and application thereof in preparing OLED 华南理工大学 2021-11-02 CN disclosed