Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197679 | 0.86 | CHRM5 (0.52) | CHRM5CHRM3SIGMAR1CA2CA12 | |
| Hydrochloric Acid SCHEMBL4961046 | 0.84 | CHRM5 (0.50) | CHRM5CHRM3SIGMAR1CA2CA12 | |
| SCHEMBL2762291 | 0.83 | SIGMAR1 (0.50) | CHRM5CHRM3SIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL62989 | 0.82 | CHRM5 (0.52) | CHRM5CHRM3SIGMAR1CA2CA12 | |
| SCHEMBL337070 | 0.82 | HSD17B10 (0.52) | CHRM5CHRM3SIGMAR1CA2CA12 | |
| SCHEMBL62990 | 0.82 | HSD17B10 (0.52) | CHRM5CHRM3SIGMAR1CA2CA12 | |
| SCHEMBL20261918 | 0.81 | CHRM5 (0.56) | CHRM5CHRM3SIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL24247411 | 0.80 | CHRM5 (0.55) | CHRM5CHRM3SIGMAR1CA2CA12 | |
| Hydrochloric Acid SCHEMBL4441607 | 0.80 | CHRM5 (0.50) | CHRM5CHRM3SIGMAR1CA2CA12 | |
| SCHEMBL8038 | 0.80 | CHRM5 (0.55) | CHRM5CHRM3SIGMAR1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228487-A1 | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND APPLICATION THEREOF | ZHEJIANG UNIVERSITY (CN) | 2024-07-11 | — | — | US | disclosed |
| EP-4306522-A1 | FUSED RING HETEROCYCLIC COMPOUND AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND APPLICATION THEREOF | Zhejiang University (CN) | 2024-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228487-A1 | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND APPLICATION THEREOF | TRPM2, TRPM8, TRPM7 | CHRM5 673/4885CHRM3 591/4885SIGMAR1 2917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.