SCHEMBL27626

SCHEMBL27626

Cc1cc(O)c(C2CCCCC2)cc1C(C)CC(c1cc(C2CCCCC2)c(O)cc1C)c1cc(C2CCCCC2)c(O)cc1C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.37
BACE1 P56817 1/20 0.37
HSP90AA1 P07900 1/20 0.34
LNPEP Q9UIQ6 1/20 0.34
PTGDR2 Q9Y5Y4 3/20 0.33
CYP2D6 P10635 2/20 0.33
CYP1A2 P05177 1/20 0.33
MAPK1 P28482 1/20 0.33
PTGDR Q13258 1/20 0.32
TP53 P04637 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
THRB P10828 3/20 0.32
THRA P10827 2/20 0.32
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31
PSMB5 P28074 1/20 0.31
ACMSD Q8TDX5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706608 1.00 NUDT1 (0.37) NUDT1BACE1HSP90AA1LNPEPPTGDR2
SCHEMBL30345205 1.00 NUDT1 (0.37) NUDT1BACE1HSP90AA1LNPEPPTGDR2
SCHEMBL29381715 1.00 NUDT1 (0.37) NUDT1BACE1HSP90AA1LNPEPPTGDR2
SCHEMBL9816539 0.99 NUDT1 (0.35) NUDT1BACE1HSP90AA1LNPEPPTGDR2
SCHEMBL10504547 0.94 NUDT1 (0.37) NUDT1BACE1HSP90AA1LNPEPPTGDR2
Phenol SCHEMBL8777717 0.93 NUDT1 (0.35) NUDT1BACE1HSP90AA1LNPEPPTGDR2
SCHEMBL16545631 0.92 NUDT1 (0.34) NUDT1BACE1HSP90AA1LNPEPPTGDR2
SCHEMBL3184220 0.91 NUDT1 (0.40) NUDT1BACE1HSP90AA1LNPEPPTGDR2
SCHEMBL8603037 0.91 ALOX15 (0.48) NUDT1BACE1LNPEPCYP2D6CYP1A2
SCHEMBL8975998 0.90 LNPEP (0.39) NUDT1BACE1HSP90AA1LNPEPPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11084308-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2021-08-10 US claimed
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 EP claimed
EP-3374195-B1 HEAT-SENSITIVE RECORDING MATERIAL KOEHLER SE AUGUST PAPIERFABRIK (DE) 2020-10-07 EP claimed
CN-108290435-B Thermosensitive recording material 奥古斯特科勒纸厂欧洲公司 2020-03-24 CN claimed
CN-108025574-B Thermal recording medium 三光株式会社 2019-04-16 CN claimed
US-20180370267-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2018-12-27 US claimed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 US claimed
EP-3374195-A1 HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2018-09-19 EP claimed
CN-108290435-A Thermal recording medium 奥古斯特科勒纸厂欧洲公司 2018-07-17 CN claimed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 US claimed
EP-0587139-A2 Heat-sensitive recording sheet MITSUBISHI PAPER MILLS, LTD. (JP) 1994-03-16 EP claimed
US-5118656-A Color developing layer of basic chromogenic dye and color developing agent hydoxy-propoxy diphenyl sulfone and phenolic substance; quality JUJO PAPER CO., LTD. (JP) 1992-06-02 US claimed
US-5110786-A Phenolic stabilizer to maintain brightness and optical density of images under high temperature conditions KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-05-05 US claimed
EP-0252691-B1 HEAT-SENSITIVE RECORD MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-09-18 EP claimed
EP-0410721-A2 Heat-sensitive recording material NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1991-01-30 EP claimed
EP-0230961-B1 PHENOL COMPOUND AND HEAT-SENSITIVE RECORDING MATERIAL ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1990-06-27 EP claimed
US-4774367-A PHENOLIC DYE DEVELOPER ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1988-09-27 US claimed
US-4771033-A CHROMOGEN, PHENOL COMPOUND, ACIDIC ACCEPTOR ON A BASE SHEET KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-09-13 US claimed
EP-0252691-A2 Heat-sensitive record material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1988-01-13 EP claimed
EP-0230961-A2 Phenol compound and heat-sensitive recording material ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-08-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 NUDT1 1166/4885BACE1 1609/4885HSP90AA1 95/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 NUDT1 1227/4885BACE1 1411/4885HSP90AA1 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.