Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.48 |
| ▸ | HTR3B | O95264 | 3/20 | 0.48 |
| ▸ | HTR3A | P46098 | 3/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811501 | 0.84 | REN (0.40) | GRM2GRM3SMN1; SMN2 | |
| SCHEMBL27729878 | 0.84 | LOXL2 (0.44) | GRM2GRM3ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL3068348 | 0.84 | GRM2 (0.47) | GRM2GRM3ALDH1A1 | |
| SCHEMBL27627069 | 0.83 | TAAR1 (0.46) | TAAR1RIPK1MEN1KMT2AIDO1 | |
| SCHEMBL27831468 | 0.83 | GRM2 (0.37) | GRM2GRM3 | |
| SCHEMBL27643671 | 0.83 | TAAR1 (0.46) | TAAR1RIPK1IDO1AGXT | |
| SCHEMBL27621459 | 0.83 | GRM2 (0.37) | GRM2GRM3 | |
| SCHEMBL27987390 | 0.83 | GRM2 (0.37) | GRM2GRM3MEN1KMT2A | |
| SCHEMBL28776111 | 0.82 | NOS1 (0.36) | GRM2GRM3KDM4E | |
| SCHEMBL26697028 | 0.82 | LMNA (0.49) | GRM2GRM3POLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1745074-A | 5-HT receptor ligands and uses thereof | PFIZER PROD INC (US) | 2006-03-08 | — | — | CN | disclosed |