Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480641 | 0.88 | ALOX15 (0.54) | ALOX15THRATHRBMEN1KMT2A | |
| SCHEMBL9729643 | 0.84 | MEN1 (0.58) | ALOX15THRATHRBMEN1KMT2A | |
| SCHEMBL8845134 | 0.82 | LTA4H (0.54) | SOS1ALOX15THRATHRBLTA4H | |
| SCHEMBL25876566 | 0.81 | THRA (0.50) | SOS1ALOX15THRATHRBPDE4A | |
| SCHEMBL3324325 | 0.80 | THRB (0.51) | ALOX15THRATHRBPDE4APDE4B | |
| SCHEMBL20717756 | 0.77 | ALOX15 (0.43) | ALOX15THRATHRBMEN1KMT2A | |
| SCHEMBL8652143 | 0.77 | HSP90AA1 (0.47) | SOS1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29598727 | 0.77 | — | — | |
| SCHEMBL91229 | 0.77 | — | — | |
| SCHEMBL28370725 | 0.74 | NPC1 (0.49) | SOS1ALOX15THRATHRBHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1683301-A | Fluorine containing bromo-diphenyl ether compound and its synthetic method | UNIV SICHUAN (CN) | 2005-10-19 | — | — | CN | disclosed |