Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622444 | 0.87 | SRD5A2 (0.52) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL996654 | 0.85 | ALDH1A1 (0.57) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL5211761 | 0.83 | LMNA (0.47) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL27627404 | 0.82 | CYP1A2 (0.48) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL6175924 | 0.82 | CA1 (0.50) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL27622437 | 0.82 | ALDH1A1 (0.47) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL3033421 | 0.81 | HTT (0.58) | LMNAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27315061 | 0.80 | CYP1A2 (0.49) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL18605288 | 0.78 | MEN1 (0.46) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL27622448 | 0.76 | POLB (0.51) | LMNARECQLALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1668603-A | Pyridazin-3(2h)-one derivatives as PDE4 inhibitors | ALMIRALL PRODESFARMA SA (ES) | 2005-09-14 | — | — | CN | disclosed |