Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622448 | 0.86 | POLB (0.51) | HTTLMNAGAAALDH1A1MAPT | |
| SCHEMBL996654 | 0.84 | ALDH1A1 (0.57) | LMNAGAAALDH1A1MAPTRECQL | |
| SCHEMBL3038660 | 0.83 | HTT (0.69) | CYP1A2CYP2C19HTTLMNAALDH1A1 | |
| SCHEMBL27627423 | 0.82 | LMNA (0.46) | HTTLMNAGAAALDH1A1MAPT | |
| SCHEMBL27641421 | 0.81 | LMNA (0.46) | HTTLMNAGAAALDH1A1MAPT | |
| SCHEMBL27622444 | 0.76 | SRD5A2 (0.52) | HTTLMNAGAAALDH1A1MAPT | |
| SCHEMBL5211761 | 0.75 | LMNA (0.47) | CYP2C19HTTLMNAGAAALDH1A1 | |
| SCHEMBL4594713 | 0.73 | GPBAR1 (0.62) | HTTLMNAGAAALDH1A1GPBAR1 | |
| SCHEMBL27674488 | 0.73 | IGFBP3 (0.45) | CYP1A2CYP2C19GAAALDH1A1IGFBP3 | |
| SCHEMBL6175924 | 0.71 | CA1 (0.50) | CYP2C19HTTLMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1668603-A | Pyridazin-3(2h)-one derivatives as PDE4 inhibitors | ALMIRALL PRODESFARMA SA (ES) | 2005-09-14 | — | — | CN | disclosed |