Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622437 | 0.85 | ALDH1A1 (0.47) | CA1CA2ALDH1A1LMNAMAPT | |
| SCHEMBL27622444 | 0.84 | SRD5A2 (0.52) | ALDH1A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL1374393 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL996654 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL27627423 | 0.82 | LMNA (0.46) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL27323098 | 0.81 | HIF1A (0.53) | ALDH1A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL9429244 | 0.81 | NPC1 (0.56) | ALDH1A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL5211761 | 0.80 | LMNA (0.47) | ALDH1A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL27641421 | 0.75 | LMNA (0.46) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL2777180 | 0.75 | PTGS2 (0.60) | ALDH1A1LMNASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575926-A1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004058729-A1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | ALMIRALL PRODESFARMA SA (ES) | 2004-07-15 | — | — | WO | disclosed |