Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 4/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.37 |
| ▸ | FABP3 | P05413 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | PER2 | O15055 | 2/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772278 | 0.70 | LMNA (0.50) | KDM4ECYP1A2CYP2C19POLBALDH1A1 | |
| SCHEMBL6533272 | 0.69 | CYP1A2 (0.40) | KDM4ECYP1A2CYP2C19POLBFABP4 | |
| SCHEMBL9608608 | 0.68 | FABP4 (0.44) | KDM4ECYP1A2CYP2C19POLBFABP4 | |
| SCHEMBL9908935 | 0.68 | POLB (0.47) | KDM4EPOLBFABP4FABP5FABP3 | |
| SCHEMBL28018005 | 0.67 | FABP4 (0.50) | KDM4ECYP1A2CYP2C19POLBFABP4 | |
| SCHEMBL28824473 | 0.67 | GPR3 (0.43) | KDM4ECYP1A2CYP2C19POLBALDH1A1 | |
| Ethane SCHEMBL28213584 | 0.67 | PER2 (0.49) | KDM4EPOLBBACE1PER2CRY1 | |
| SCHEMBL19583449 | 0.66 | GPR3 (0.46) | KDM4ECYP1A2CYP2C19POLBFABP4 | |
| SCHEMBL17224372 | 0.66 | FABP4 (0.57) | KDM4EFABP4FABP5FABP3HDAC6 | |
| SCHEMBL17394563 | 0.65 | GPR3 (0.50) | KDM4ECYP1A2CYP2C19POLBFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2221347-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-2179996-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-04-28 | — | — | EP | disclosed |
| US-7018431-B2 | Sulfonated diarylrhodamine dyes | APPLERA CORPORATION (US) | 2006-03-28 | — | — | US | disclosed |
| US-20040096397-A1 | Sulfonated diarylrhodamine dyes | APPLERA CORPORATION (US) | 2004-05-20 | — | — | US | disclosed |
| EP-1339798-A2 | SULFONATED DIARYLRHODAMINE DYES | Applera Corporation (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6583168-B1 | Fluorescent labels of nucleosides, nucleotides, polynucleotides, and polypeptides in nucleic acid analysis | APPLERA CORPORATION | 2003-06-24 | — | — | US | disclosed |
| WO-2002044416-A2 | SULFONATED DIARYLRHODAMINE DYES AS FLUORESCENT LABELS | APPLERA CORPORATION (US) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096397-A1 | Sulfonated diarylrhodamine dyes | POLL, DUT, DPYD | KDM4E 4647/4885CYP1A2 3635/4885CYP2C19 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.