Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260481 | 0.89 | LIPG (0.45) | LIPGGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL27653930 | 0.78 | NOTUM (0.44) | GABRA1GABRG2GABRB3GABRA3POLB | |
| SCHEMBL14263093 | 0.75 | TRPV1 (0.44) | LIPGALDH1A1CYP1A2 | |
| SCHEMBL34469884 | 0.73 | PTGS2 (0.48) | LIPGALDH1A1NOTUMSMN1; SMN2CYP2C19 | |
| SCHEMBL9458564 | 0.71 | ALDH1A1 (0.49) | GABRA1GABRG2GABRB3GABRA3ALDH1A1 | |
| SCHEMBL27633470 | 0.69 | SMN1; SMN2 (0.47) | GABRA1GABRG2GABRB3GABRA3MMP1 | |
| SCHEMBL27633483 | 0.69 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL34470252 | 0.67 | MAP4K4 (0.44) | — | |
| SCHEMBL9635530 | 0.67 | ALDH1A1 (0.50) | POLBALDH1A1HSD17B10ATMCYP2C9 | |
| SCHEMBL3494668 | 0.67 | MAOA (0.41) | NR4A2POLBALDH1A1L3MBTL1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1829697-A | Aryl-heteroaromatic products, compositions containing same and use thereof | AVENTIS PHARMA SA (FR) | 2006-09-06 | — | — | CN | claimed |
| CN-100427472-C | Aryl-heteroaromatic compounds, compositions containing them and their use | AVENTIS PHARMA SA (FR) | 2008-10-22 | — | — | CN | disclosed |
| CN-1829697-A | Aryl-heteroaromatic products, compositions containing same and use thereof | AVENTIS PHARMA SA (FR) | 2006-09-06 | — | — | CN | disclosed |