SCHEMBL2763548

SCHEMBL2763548

CCO[Si](CCNc1ccc(C)cc1)(OCC)OCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
HRH3 Q9Y5N1 1/20 0.41
HTT P42858 2/20 0.38
GAA P10253 5/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
PLEC Q15149 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5684774 0.90 MAPT (0.52) MAPTHRH3HTTGAAALDH1A1
SCHEMBL554774 0.84 MAPT (0.47) MAPTHRH3GAAALDH1A1KMT2A
SCHEMBL2763057 0.81 MAPT (0.59) MAPTHRH3HTTGAAALDH1A1
SCHEMBL5685426 0.75 MAPT (0.42) MAPTHTTGAAALDH1A1MEN1
SCHEMBL134305 0.74 ALDH1A1 (0.53) MAPTHRH3ALDH1A1KMT2AL3MBTL1
SCHEMBL2855125 0.73 POLB (0.57) MAPTHTTALDH1A1MEN1POLB
SCHEMBL3198023 0.73 GAA (0.58) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL2065837 0.73 MAPT (1.00) MAPTHRH3HTTGAAALDH1A1
SCHEMBL2763549 0.72 MAPT (0.58) MAPTHTTGAAALDH1A1MEN1
SCHEMBL2116813 0.72 ALDH1A1 (0.52) MAPTHTTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2177545-A1 POLYMER FOR FORMING INSULATING FILM, COMPOSITION FOR FORMING INSULATING FILM, INSULATING FILM, AND ELECTRONIC DEVICE HAVING INSULATING FILM Sumitomo Bakelite Company Limited (JP) 2010-04-21 EP disclosed
US-20040197484-A1 Coating liquid for forming insulating film and method for producing insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-07 US disclosed