Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782835 | 0.85 | PKM (0.52) | LMNATP53RXFP1KDM4EHDAC1 | |
| SCHEMBL29154642 | 0.80 | KDM4E (0.60) | LMNATP53RXFP1KDM4ENPC1 | |
| SCHEMBL7183194 | 0.79 | MAPT (0.55) | LMNATP53RXFP1HDAC1HDAC3 | |
| SCHEMBL7853474 | 0.74 | GAA (0.51) | LMNATP53RXFP1KDM4ENPC1 | |
| SCHEMBL23643039 | 0.73 | KMT2A (0.60) | RXFP1GAAL3MBTL1MAPTKMT2A | |
| SCHEMBL4716637 | 0.73 | ALDH1A1 (0.47) | KDM4ENPC1RAB9AHSD17B10GAA | |
| SCHEMBL8399721 | 0.72 | HDAC1 (0.69) | LMNATP53KDM4ENPC1RAB9A | |
| SCHEMBL7550157 | 0.72 | ALDH1A1 (0.46) | LMNAKDM4EGAAL3MBTL1MAPT | |
| SCHEMBL31424196 | 0.72 | RAB9A (0.62) | LMNATP53KDM4ENPC1RAB9A | |
| SCHEMBL5224838 | 0.72 | RAB9A (0.62) | LMNATP53KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1708306-A | Quinazolinone compounds as calcilytics | NPS PHARMA INC (US) | 2005-12-14 | — | — | CN | disclosed |