Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617484 | 0.88 | KCNH2 (0.43) | KCNH2GAAOXER1LMNAL3MBTL1 | |
| SCHEMBL3554094 | 0.83 | KMT2A (0.42) | KMOKCNH2GAANPSR1 | |
| SCHEMBL27617492 | 0.78 | PKM (0.48) | OXER1LMNAL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL27617476 | 0.77 | PIM1 (0.38) | KCNH2TSHRHSD17B10PTGDR2 | |
| SCHEMBL27617465 | 0.73 | AKR1C3 (0.40) | KCNH2ALDH1A1PTGDR2 | |
| SCHEMBL27617460 | 0.73 | LMNA (0.40) | GAALMNAALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL28757609 | 0.72 | GAA (0.42) | KMOGAALMNAL3MBTL1TSHR | |
| SCHEMBL22441037 | 0.71 | PTGDR2 (0.56) | KMOAKR1B1PTGDR2 | |
| SCHEMBL28757608 | 0.71 | KCNH2 (0.34) | KCNH2TSHRAKR1B1PTGDR2 | |
| SCHEMBL2475378 | 0.70 | NOTUM (0.45) | KCNH2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1720227-A | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LTD (IN) | 2006-01-11 | — | — | CN | disclosed |