Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1333179 | 0.80 | HTT (0.54) | SMN1; SMN2KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL28120658 | 0.80 | KMT2A (0.41) | LMNASMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL6123415 | 0.78 | KDM4E (0.41) | LMNASMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL27617465 | 0.78 | AKR1C3 (0.40) | KDM4EELANEALDH1A1 | |
| SCHEMBL27617460 | 0.78 | LMNA (0.40) | LMNASMN1; SMN2ELANEKMT2AALDH1A1 | |
| SCHEMBL27617484 | 0.78 | KCNH2 (0.43) | LMNAKDM4EOXER1ELANEALDH1A1 | |
| SCHEMBL27636554 | 0.78 | KMO (0.38) | LMNAOXER1ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL4794896 | 0.76 | SMN1; SMN2 (0.77) | LMNASMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL10842060 | 0.76 | KMT2A (0.67) | LMNASMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL24877826 | 0.74 | HTR6 (0.56) | OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104125956-A | Cyclic amides as inhibitors of 11-beta-hydroxysteroid dehydrogenase and uses thereof | CONNEXIOS LIFE SCIENCES PVT LTD | 2014-10-29 | — | — | CN | disclosed |
| CN-102249981-A | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LTD | 2011-11-23 | — | — | CN | disclosed |
| CN-1720227-A | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LTD (IN) | 2006-01-11 | — | — | CN | disclosed |