Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27636554 | 0.88 | KMO (0.38) | KCNH2ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL2475378 | 0.83 | NOTUM (0.45) | KCNH2KDM4EGFERCA1CA2 | |
| SCHEMBL27617460 | 0.82 | LMNA (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL27617465 | 0.82 | AKR1C3 (0.40) | KCNH2ALDH1A1KDM4EPTGDR2ELANE | |
| SCHEMBL27617492 | 0.78 | PKM (0.48) | ALDH1A1KDM4EELANEPOLBOXER1 | |
| SCHEMBL17829607 | 0.77 | MAP3K14 (0.44) | KCNH2ALDH1A1KDM4EPTGDR2LMNA | |
| SCHEMBL27617476 | 0.77 | PIM1 (0.38) | KCNH2TSHRHSD17B10PTGDR2 | |
| SCHEMBL28757608 | 0.74 | KCNH2 (0.34) | KCNH2TSHRPTGDR2 | |
| SCHEMBL27636576 | 0.72 | ALDH1A1 (0.47) | KCNH2ALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL3554094 | 0.70 | KMT2A (0.42) | KCNH2KDM4ECA1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1720227-A | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LTD (IN) | 2006-01-11 | — | — | CN | disclosed |