SCHEMBL27640697

SCHEMBL27640697

CC(C)(C)c1cccc(CS(=O)(=O)O)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.55
GABRA1 P14867 2/20 0.48
GABRB2 P47870 2/20 0.48
ATM Q13315 1/20 0.47
NPSR1 Q6W5P4 1/20 0.41
ALOX12 P18054 1/20 0.41
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PTPN5 P54829 1/20 0.38
HSPA5 P11021 2/20 0.37
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
ALOX5 P09917 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787225 0.85 CA2 (0.43) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL57139 0.83 GABRA1 (0.67) CA2GABRA1GABRB2ATMNPSR1
Propane SCHEMBL28225674 0.81 GABRA1 (0.64) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL27661263 0.81 GABRA1 (0.71) GABRA1GABRB2PTPN5
SCHEMBL2935552 0.79 CA2 (0.67) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL16266135 0.77 CA2 (0.46) CA2GABRA1GABRB2NPSR1ALOX12
SCHEMBL10706992 0.77 CA2 (0.64) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL6858500 0.76 CA2 (0.61) CA2GABRA1GABRB2NPSR1ALOX12
SCHEMBL27555820 0.76 CA2 (0.61) CA2GABRA1GABRB2ATMNPSR1
SCHEMBL27661203 0.76 ALDH1A1 (0.50) CA2GABRA1GABRB2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1856536-A Process for improving color of polycondensates CIBA SC HOLDING AG (CH) 2006-11-01 CN disclosed