Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467813 | 0.87 | ESR1 (0.44) | ESR1MEN1KMT2ARARBRARG | |
| SCHEMBL3468563 | 0.84 | MMP3 (0.47) | ESR1ESR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3075044 | 0.82 | ESR1 (0.50) | ESR1ESR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6511368 | 0.82 | BCAT2 (0.42) | ESR1MEN1KMT2ASMN1; SMN2SCN1A | |
| SCHEMBL3468373 | 0.82 | SLC6A3 (0.49) | ESR1SCN1ASCN2ASCN3ATSHR | |
| SCHEMBL3468030 | 0.79 | ESR1 (0.40) | ESR1ESR2ABL1ABCB1BCR | |
| SCHEMBL3468408 | 0.79 | ESR1 (0.56) | ESR1ESR2MEN1KMT2ASMN1; SMN2 | |
| Gsk-232802 SCHEMBL3467757 | 0.74 | ESR1 (0.55) | ESR1MEN1KMT2ASMN1; SMN2RARB | |
| SCHEMBL3468080 | 0.73 | ESR1 (0.51) | ESR1MEN1KMT2ABCL2L1RARB | |
| SCHEMBL6507023 | 0.73 | ESR1 (0.36) | ESR1ESR2MEN1KMT2ABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1856461-A | Cycloalkylene compounds as estrogen receptor modulators | SMITHKLINE BEECHAM CORP (US) | 2006-11-01 | — | — | CN | disclosed |