Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612917 | 0.90 | LMNA (0.58) | LMNACYP2C19HIF1A | |
| SCHEMBL8378595 | 0.85 | LMNA (0.60) | LMNACYP2C19HIF1A | |
| SCHEMBL8375497 | 0.82 | LMNA (0.56) | LMNACYP2C19HIF1A | |
| SCHEMBL619948 | 0.82 | LMNA (0.60) | LMNACYP2C19HIF1A | |
| SCHEMBL14310826 | 0.79 | LMNA (0.83) | LMNACYP2C19HIF1A | |
| SCHEMBL8377985 | 0.78 | LMNA (0.45) | LMNACYP2C19HIF1A | |
| SCHEMBL1744064 | 0.76 | LMNA (0.44) | LMNACYP2C19HIF1A | |
| SCHEMBL1742159 | 0.76 | LMNA (0.42) | LMNACYP2C19HIF1A | |
| SCHEMBL1744046 | 0.75 | LMNA (0.53) | LMNACYP2C19HIF1A | |
| SCHEMBL8382143 | 0.75 | LMNA (0.49) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738596-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2017-08-22 | — | — | US | disclosed |
| US-20150191422-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2015-07-09 | — | — | US | disclosed |
| US-8920780-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2014-12-30 | — | — | US | disclosed |
| EP-2178568-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2014-07-02 | — | — | EP | disclosed |
| US-20100322868-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-12-23 | — | — | US | disclosed |
| EP-2178568-A2 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009008734-A2 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191422-A1 | CONTRAST AGENTS | SSTR3, INSR, INSRR | LMNA 1656/4885CYP2C19 3523/4885HIF1A 1391/4885 |
| US-20100322868-A1 | CONTRAST AGENTS | SSTR3, INSR, INSRR | LMNA 1656/4885CYP2C19 3523/4885HIF1A 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.